Research Articles:

  1. T Ergünay, Ö Ayhan, A B Celen, P Georgiadou, E Pekbilir, YT Abaci, D Yesildag, M Rettel, U Sobhiafshar, A Ogmen, NCT Emre, U Sahin (2022) Sumoylation of Cas9 at Lysine 848 Regulates Protein Stability and DNA Binding. Life Science Alliance 5 (4) e202101078; doi: 10.26508/lsa.202101078
  2. A Weilemann , M Grau , T Erdmann , O Merkel , U Sobhiafshar , I Anagnostopoulos , M Hummel , A Siegert , C Hayford , H Madle , B Wollert-Wulf , I Fichtner , B Dörken , S Dirnhofer , S Mathas , M Janz , N. C.T Emre , A Rosenwald , G Ott , P Lenz , A Tzankov , G Lenz (2015) Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma. Blood , 125 (1) 124-132 PMID: 25359993
  3. C Praetorius, C Grill, SN Stacey, AM Metcalf, DU Gorkin, KC Robinson, EV Otterloo, RSQ Kim, K Bergsteinsdottir, MH Ogmundsdottir, E Magnusdottir, PJ Mishra, SR Davis, T Guo, MR Zaidi, AS Helgason, MI Sigurdsson, PS Meltzer, G Merlino, V Petit, L Larue, SK Loftus, DR Adams, U Sobhiafshar, NCT Emre, WJ Pavan, R Cornell, AG Smith, AS McCallion, DE Fisher, K Stefansson, RA Sturm, E Steingrimsson (2013) A Polymorphism in IRF4 Affects Human Pigmentation through a Tyrosinase-Dependent MITF/TFAP2A Pathway. Cell.155:1022-1033 PMID: 24267888
  4. L Lamy, VN Ngo, NCT Emre, AL Shaffer et al (2013) Control of Autophagic Cell Death by Caspase-10 in Multiple Myeloma. Cancer Cell. 23:435-449. PMID: 23541952 Preview in Cancer Cell: “Autophagy in Multiple Myeloma: What Makes You Stronger Can Also Kill You”
  5. Y Yang*, AL Shaffer*, NCT Emre*, M Ceribelli et al (2012) Exploiting Synthetic Lethality for the Therapy of ABC Diffuse Large B Cell Lymphoma. Cancer Cell. 21:723-37 (*: equal contribution) PMID:22698399.
  6. L Rui, NCT Emre, MJ Kruhlak, HJ Chung et al (2010) Cooperative epigenetic modulation by cancer amplicon genes. Cancer Cell. 18:590-605.PMID:21156283. Preview in Cancer Cell: “Partners in Crime: Genes within an Amplicon Collude to Globally Deregulate Chromatin in Lymphoma”
  7. B Sayan, NCT Emre, MB Irmak, M Öztürk, R Çetin-Atalay (2009) Nuclear exclusion of p33ING1b tumor suppressor protein: explored in HCC cells using a new highly specific antibody. Hybridoma, 28:1-6 PMID: 19132896
  8. AL Shaffer, NCT Emre, L Lamy, VN Ngo, G Wright, W Xiao, J Powell, S Dave, X Yu, H Zhao, Y Zeng, B Chen, J Epstein, LM Staudt (2008) IRF4 addiction in multiple myeloma. Nature, 454: 226-31. PMCID:2542904. Editor’s summary   News and Views in Nature: “Cancer: An unexpected addiction”
  9. G Lenz, GW Wright, NCT Emre, H Kohlhammer et al  (2008) Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways. Proc Natl Acad Sci U S A, 105:13520-5.  PMCID:2533222
  10. NCT Emre, K Ingvarsdottir, A Wyce, A Wood, NJ Krogan, KW Henry, K Li, JF Greenblatt, R Marmorstein, A Shilatifard, SL Berger (2005) Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere proximal Sir2 association and gene silencing. Mol Cell, 17: 585-594. PMID:15721261. News release: “Enzyme shown to help protect genomic stability”
  11. K Ingvarsdottir*, NJ Krogan*, NCT Emre*, A Wyce, JF Greenblatt, SL Berger (2005) H2B ubiquitin protease Ubp8 and Sgf11 are a discrete functional module within the S. cerevisiae SAGA complex. Mol Cell Biol, 25:1162-1172. (*: equal contribution) PMCID:544016
  12. KW Henry, A Wyce, W-S Lo, LJ Duggan, NCT Emre, C-F Kao, L Pillus, A Shilatifard, MA Osley, SL Berger (2003) Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes Dev, 21:2648-63. PMCID:280615.
  13. H Santos-Rosa, R Schneider, AJ Bannister, J Sherriff, BE Bernstein, NCT Emre, SL Schreiber, J Mellor, and T Kouzarides (2002). Active genes are tri-methylated at K4 of histone H3. Nature, 419:407-411. PMID:12353038.
  14. WS Lo, L Duggan, NCT Emre, R Belotserkovskya, WS Lane, R Shiekhattar, SL Berger (2001)  Snf1–a histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription. Science, 293:1142-6.PMID:11498592

Review/Method Articles/Chapters:

  1. DJ Klionsky et al. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) Autophagy, 17(1):1-382. doi: 10.1080/15548627.2020.1797280
  2.  NCT Emre (2018) Epigenetik ve Kanser, book chapter in Kanserin Moleküler Biyolojisi (Ed. Y Baran; Kısayol Yayıncılık)
  3. AL Shaffer, NCT Emre, PB Romesser, LM Staudt (2009) IRF4: Immunity. Malignancy! Therapy? Clin Cancer Res. 15:2954-61. PMCID:2790720.
  4. NCT Emre, SL Berger (2006) Histone post-translational modifications regulate transcription and telomeric silencing in S. cerevisiae. Ernst Schering Res Found Workshop, 57:127-53. PMID: 16568953
  5. NCT Emre, SL Berger (2004) Histone H2B Ubiquitylation and Deubiquitylation in Genomic Regulation. Cold Spring Harbor Symposia on Quantitative Biology, 69: 289-299. PMID:16117661

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